Our mission is to develop replacements for the use of animals in research and testing. Replacements based on the best science. Replacements that are cheaper and faster. Replacements that are better predictors of the safety of the chemicals in our environment that we are exposed to everyday. Replacements that are better predictors of the safety and efficacy of new drugs being developed to treat unmet medical needs.

We are motivated by the fact that:

1. animal testing is slow, expensive and not predictive of the human response;
2. tens of thousands of synthetic chemicals in our environment and households have not been adequately tested;
3. government agencies around the world have begun the banning of animal testing;
4. most new drugs fail in clinical trials due to unanticipated toxicity despite extensive testing in
   animals; and
5. more physiologically relevant models are needed for the testing and discovery of new drugs.

We are a collaborative and scholarly environment for research, teaching and the training of the next generation. With support from the government, industry partners and philanthropic sources, we are focused on the innovations needed to understand the fundamental characteristics of health and disease with the goal of identifying alternatives to animals in research and testing.